Planar cell polarity (PCP) is generated by the restricted localization of membrane-bound multiprotein complexes, but how they are trafficked to the correct location is unknown. Here, the authors show that the GTPase ARF1 and the AP-1 adaptor complex are major regulators of PCP protein trafficking in vivo.
- Jose Maria Carvajal-Gonzalez
- Sophie Balmer
- Marek Mlodzik
