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Advanced filters: Author: Brian Ibeabuchi Clear advanced filters
  • Lee, Barone et al. engineered a mutant form of LSD1, Y391K, which renders the nucleosome demethylase activity of LSD1 insensitive to Lys14 acetylation of histone H3, providing a useful tool to illuminate the functional consequences of disconnecting histone modification crosstalk.

    • Kwangwoon Lee
    • Marco Barone
    • Philip A. Cole
    Research
    Nature Chemical Biology
    Volume: 21, P: 227-237