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Showing 1–7 of 7 results

Advanced filters: Author: Brian P. Danysh Clear advanced filters

Developmental mosaicism underlying EGFR-mutant lung cancer presenting with multiple primary tumors

Burr et al. analyze multiple primary EGFR-mutant lung tumors from ten patients and define developmental mosaicism as a mechanism underlying multiple tumor presentation in this setting.

Risa Burr
Ignaty Leshchiner
Daniel A. Haber
ResearchOpen Access15 Oct 2024
Nature Cancer

Volume: 5, P: 1681-1696
Distinct cellular dynamics associated with response to CAR-T therapy for refractory B cell lymphoma

Single-cell transcriptomics analyses of pretreatment and post-treatment peripheral blood mononuclear cells from patients treated with CD19 chimeric antigen receptor (CAR)-T products reveal a role for CAR-T regulatory cells in treatment relapse.

Nicholas J. Haradhvala
Mark B. Leick
Marcela V. Maus
Research12 Sept 2022
Nature Medicine

Volume: 28, P: 1848-1859
Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome

Integrative genomic and transcriptomic analyses reveal molecular events defining Richter transformation from CLL, and highlight the potential of cell-free DNA for early detection.

Erin M. Parry
Ignaty Leshchiner
Catherine J. Wu
Research09 Jan 2023
Nature Medicine

Volume: 29, P: 158-169
Author Correction: Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers

Aparna R. Parikh
Ignaty Leshchiner
Ryan B. Corcoran
Amendments and Corrections19 Nov 2019
Nature Medicine

Volume: 25, P: 1949
Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers

Direct prospective comparison of circulating tumor DNA and tissue biopsy sequencing shows the superiority of liquid biopsies for capturing clinically relevant alterations mediating resistance to targeted therapies in cancer patients.

Aparna R. Parikh
Ignaty Leshchiner
Ryan B. Corcoran
Research09 Sept 2019
Nature Medicine

Volume: 25, P: 1415-1421
Src-mediated regulation of the PI3K pathway in advanced papillary and anaplastic thyroid cancer

Thomas C. Beadnell
Kelsey W. Nassar
Rebecca E. Schweppe
ResearchOpen Access28 Feb 2018
Oncogenesis

Volume: 7, P: 1-14
Matrilysin/MMP-7 Cleavage of Perlecan/HSPG2 Complexed with Semaphorin 3A Supports FAK-Mediated Stromal Invasion by Prostate Cancer Cells

Brian J. Grindel
Jerahme R. Martinez
Mary C. Farach-Carson
ResearchOpen Access08 May 2018
Scientific Reports

Volume: 8, P: 1-14