Authors utilise a metabolomics approach to identify microbial-derived metabolites that synergistically inhibit urease activity in Proteus mirabilis, a cause of urease-induced kidney stones. They reveal that two metabolites prevented urinary catheter encrustation and improved antimicrobial efficacy against catheter biofilm.
- L. Beryl Guterman
- Madalyn Motsay
- Chelsie E. Armbruster
