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Showing 1–4 of 4 results
Advanced filters: Author: Bright Adu Clear advanced filters

  • In this genomic epidemiology study from Ghana, the authors sequence ~1,000 SARS-CoV-2 whole genomes from March 2020 to September 2021. They describe changes in the predominant circulating lineages over time and infer how variants of concern were likely introduced into the country.

    • Collins M. Morang’a
    • Joyce M. Ngoi
    • Gordon A. Awandare
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-11

  • High-income countries have a wealth of genomics expertise that can be rapidly activated to deal with disease threats. African countries should invest in a federated data-management system for genomics epidemiology to deal with such threats better.

    • Alan Christoffels
    • Gerald Mboowa
    • Yenew Kebede Tebeje
    Comments & Opinion
    Nature Medicine
    Volume: 29, P: 1052-1055

  • FcγR-mediated signaling by cytophilic IgG against Plasmodium falciparum merozoites triggers ROS generation predominantly in neutrophils as a mechanism contributing to naturally acquired immunity against malaria in endemic regions in Ghana and India.

    • Ebenezer Addo Ofori
    • Asier Garcia-Senosiain
    • Michael Theisen
    ResearchOpen Access
    Communications Biology
    Volume: 6, P: 1-11

  • Garcia-Senosiain et al developed an in vitro opsonic phagocytosis (OP) assay using peripheral blood leukocytes that enabled quantification of the contribution of each phagocytic cell type in the OP of Plasmodium falciparum blood-stage merozoites, which have been associated with malaria protection. Using patient samples from Ghana and India, they demonstrate that peripheral blood neutrophils are the main phagocytes of P. falciparum blood-stage merozoites

    • Asier Garcia-Senosiain
    • Ikhlaq Hussain Kana
    • Michael Theisen
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-10