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Showing 1–2 of 2 results
Advanced filters: Author: Bror Alstermark Clear advanced filters
  • Cervical propriospinal neurons (PNs) form a genetically accessible subclass of V2a interneurons that convey both premotor output and precerebellar copy signals; their ablation in mice impairs reaching movements selectively, and activation of their internal copy projection recruits a rapid cerebellar feedback loop that modulates forelimb movement.

    • Eiman Azim
    • Juan Jiang
    • Thomas M. Jessell
    Research
    Nature
    Volume: 508, P: 357-363
  • A new double-infection technique with viral vectors is used to interrupt transmission through the propriospinal neurons (PNs) in macaque monkeys, and this is found to impair reach and grasp movements, revealing a critical role for the PN-mediated pathway in the control of hand dexterity.

    • Masaharu Kinoshita
    • Ryosuke Matsui
    • Tadashi Isa
    Research
    Nature
    Volume: 487, P: 235-238