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Showing 1–6 of 6 results
Advanced filters: Author: Bruce A Molitoris Clear advanced filters

  • The Acute Kidney Injury Network (AKIN) met in Amsterdam, The Netherlands, in September 2005. At the 2-day meeting, participants in this multidisciplinary collaboration proposed a standard definition, and scheme for the classification, of AKI. Widespread adoption of these standards, presented here by members of the AKIN working group, would help to advance the study of this condition, and improve patient outcomes.

    • Bruce A Molitoris
    • Adeera Levin
    • Sudhir V Shah
    Reviews
    Nature Clinical Practice Nephrology
    Volume: 3, P: 439-442

  • In this Viewpoint, five members of theNature Reviews Nephrologyadvisory board reflect on the progress and frustrations of the past decade in basic and clinical nephrology research. They comment on areas where effort and money should be invested and the challenges that remain to be overcome, as well as give their predictions for progress in the next decade.

    • Jürgen Floege
    • Robert H. Mak
    • Pierre Ronco
    Reviews
    Nature Reviews Nephrology
    Volume: 11, P: 677-687

  • The difficulties that are currently inherent in early diagnosis of acute kidney injury could be overcome by the introduction of biomarkers into routine clinical practice. Here, Bruce Molitoris and colleagues provide an update of the status of development of biomarkers for this indication. Transcriptomics, proteomics, and gene array and imaging technologies are just some of the methods being harnessed to drive the discovery process. Subsequent validation in high quality clinical trials will be essential.

    • Bruce A Molitoris
    • Vyacheslav Y Melnikov
    • Jonathan Himmelfarb
    Reviews
    Nature Clinical Practice Nephrology
    Volume: 4, P: 154-165

  • The ACP has published 'weak' guidelines for screening patients for kidney disease based on limited or no data, which could harm patients with undiagnosed or progressive kidney disease. As kidney experts weren't involved in the development of these guidelines, what should all health professionals know about screening for kidney disease?

    • Bruce A. Molitoris
    News & Views
    Nature Reviews Nephrology
    Volume: 10, P: 6-8

  • Ischemia is the most common cause of acute kidney injury (AKI) in hospitalized patients. The authors of this Review describe the morphological and functional responses of kidney cells to ischemic injury. They also outline the characteristics of patients who are at highest risk of developing ischemic AKI and discuss therapeutic strategies for the prevention and management of this condition.

    • Asif A. Sharfuddin
    • Bruce A. Molitoris
    Reviews
    Nature Reviews Nephrology
    Volume: 7, P: 189-200