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Showing 1–4 of 4 results
Advanced filters: Author: Bruce Bebo Clear advanced filters

  • Approximately half of the people currently with multiple sclerosis (MS) are ≥50 years of age, yet guidelines for management of MS in older age are lacking. This Consensus statement presents the outcomes of an International Advisory Committee on Clinical Trials (IACCT) in MS workshop on ageing and MS, including recommendations for advancing research, care and awareness.

    • Anneke van der Walt
    • Eva M. M. Strijbis
    • Yinan Zhang
    Reviews
    Nature Reviews Neurology
    Volume: 21, P: 432-448

  • In this Roadmap, Marrie and colleagues set out the steps needed to improve our understanding of the multiple sclerosis (MS) prodrome and develop standardized criteria for identifying individuals with prodromal MS, thereby facilitating trials of interventions that could slow progression to classical MS.

    • Ruth Ann Marrie
    • Mark Allegretta
    • Helen Tremlett
    Reviews
    Nature Reviews Neurology
    Volume: 18, P: 559-572

  • Richard Trembath and colleagues report a meta-analysis of genome-wide association studies for psoriasis, including 2 cohorts genotyped on the custom Immunochip array, in a total of 10,588 cases and 22,806 controls. They identify 15 new susceptibility loci and refine signals in previously known loci, highlighting a role for innate host defense in susceptibility to psoriasis.

    • Lam C Tsoi
    • Sarah L Spain
    • Richard C Trembath
    Research
    Nature Genetics
    Volume: 44, P: 1341-1348