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Showing 1–3 of 3 results
Advanced filters: Author: Burkhard Poeck Clear advanced filters

  • Visual orientation in a complex environment requires a memory for targets' spatial position, in case they become temporarily out of sight, a faculty known as 'spatial working memory' in vertebrates. Use of a virtual-reality arena to present visual targets to walking fruit flies shows that insects share the faculty. Cell-specific gene rescue in learning mutants, ablation of brain areas and neuron-specific silencing experiments revealed that a distinct subset of neurons in the central brain is required for a spatial working memory in flies.

    • Kirsa Neuser
    • Tilman Triphan
    • Roland Strauss
    Research
    Nature
    Volume: 453, P: 1244-1247

  • Features of major depressive disorder including lack of motivation, sleep disruption and cognitive deficit have been modelled in rodents. Here, the authors develop a new method to elicit a depression-like state inDrosophila, and uncover separable roles for different serotonin receptors in depression-like behaviour.

    • Ariane-Saskia Ries
    • Tim Hermanns
    • Roland Strauss
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-11

  • One of the most abundant modifications found in messenger RNAs is N6-methyladenosine (m6A); here, this modification is shown to alter gene expression during sex determination and affect neuronal functions and behaviour in Drosophila via the m6A reader protein YT521-B.

    • Tina Lence
    • Junaid Akhtar
    • Jean-Yves Roignant
    Research
    Nature
    Volume: 540, P: 242-247