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Advanced filters: Author: Cécile Garnaud Clear advanced filters

  • BET proteins bind chromatin through their bromodomains (BDs) to regulate transcription and chromatin remodelling. Here, the authors show that the BET protein Bdf1 is essential for the fungal pathogenCandida albicans, and report compounds that inhibit the Bdf1 BDs with high selectivity over human BDs.

    • Flore Mietton
    • Elena Ferri
    • Carlo Petosa
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-15