Mammalian female meiosis is error prone, with error rates increasing with age. Here Touati et al. show that the spindle assembly checkpoint (SAC) protein BubR1, which decreases with age, has multiple roles in meiosis I by controlling SAC, stabilizing the mitotic spindle and timing the onset of anaphase I.
- Sandra A. Touati
- Eulalie Buffin
- Katja Wassmann
