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British Journal of Cancer (65)
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Showing 1–50 of 75 results

Advanced filters: Author: C Twelves Clear advanced filters

Variation in survival of women with breast cancer: Health Board remains a factor at 10 years

C J Twelves
C S Thomson
D H Brewster
ResearchOpen Access28 Aug 2001
British Journal of Cancer

Volume: 85, P: 637-640
Weekly doxorubicin and continuous infusional 5-fluorouracil for advanced breast cancer

H Gabra
DA Cameron
RCF Leonard
Research01 Dec 1996
British Journal of Cancer

Volume: 74, P: 2008-2012
Pharmacoeconomic analysis of adjuvant oral capecitabine vs intravenous 5-FU/LV in Dukes' C colon cancer: the X-ACT trial

J Cassidy
J-Y Douillard
L P Garrison
ResearchOpen Access18 Apr 2006
British Journal of Cancer

Volume: 94, P: 1122-1129
Which endpoints should we use in evaluating the use of novel fluoropyrimidine regimens in colorectal cancer?

C J Twelves
J Cassidy
ReviewsOpen Access07 Jun 2002
British Journal of Cancer

Volume: 86, P: 1670-1676
Capecitabine-associated hand–foot–skin reaction is an independent clinical predictor of improved survival in patients with colorectal cancer

R-D Hofheinz
V Heinemann
S Stintzing
ResearchOpen Access02 Oct 2012
British Journal of Cancer

Volume: 107, P: 1678-1683
The clinical and economic benefits of capecitabine and tegafur with uracil in metastatic colorectal cancer

S E Ward
E Kaltenthaler
M T Seymour
ResearchOpen Access27 Jun 2006
British Journal of Cancer

Volume: 95, P: 27-34
Uracil/ftorafur/leucovorin combined with irinotecan (TEGAFIRI) or oxaliplatin (TEGAFOX) as first-line treatment for metastatic colorectal cancer patients: results of randomised phase II study

E Bajetta
M Di Bartolomeo
A Iop
ResearchOpen Access23 Jan 2007
British Journal of Cancer

Volume: 96, P: 439-444
Is oxaliplatin combined with weekly bolus 5-fluorouracil and leucovorin an option for stage II and III colon cancer?

Chris Twelves
Comments & Opinion20 Nov 2007
Nature Clinical Practice Oncology

Volume: 5, P: 72-73
p53 mutation, deprivation and poor prognosis in primary breast cancer

L Baker
P R Quinlan
A M Thompson
ResearchOpen Access26 Jan 2010
British Journal of Cancer

Volume: 102, P: 719-726
A phase I and pharmacokinetic study of the combination of capecitabine and docetaxel in patients with advanced solid tumours

L C Pronk
P Vasey
C Twelves
ResearchOpen Access06 Jun 2000
British Journal of Cancer

Volume: 83, P: 22-29
In pursuit of excellence for patients with cancer: the Scottish Cancer Therapy Network model

P L Stroner
D H Brewster
S B Kaye
ReviewsOpen Access12 Mar 1999
British Journal of Cancer

Volume: 79, P: 1641-1645
Targeting the protein kinase C family: are we there yet?

The protein kinase C family of serine/threonine kinases is implicated in tumorigenesis. Although targeting these kinases for cancer therapy is not a new idea, the results from clincal trials with several agents have been disapointing. Why is this?

Helen J. Mackay
Christopher J. Twelves
Reviews01 Jul 2007
Nature Reviews Cancer

Volume: 7, P: 554-562
Oral fluoropyrimidines among the new drugs for patients with metastatic breast cancer

R C F Leonard
ReviewsOpen Access29 May 2001
British Journal of Cancer

Volume: 84, P: 1437-1442
Clinical and immunopathological evaluation and its comparison with IHC consensus molecular subtypes of colorectal cancer

Eduardo Feliciangeli
Ana Albaladejo-González
Ginés Luengo-Gil
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-22
Idarubicinol myelotoxicity: a comparison of in vitro data with clinical outcome in patients treated with high-dose idarubicin

C Corsini
M Ghielmini
G Martinelli
ResearchOpen Access07 Jan 2000
British Journal of Cancer

Volume: 82, P: 524-528
Antiproliferative activity of PEP005, a novel ingenol angelate that modulates PKC functions, alone and in combination with cytotoxic agents in human colon cancer cells

K A Benhadji
M Serova
E Raymond
ResearchOpen Access25 Nov 2008
British Journal of Cancer

Volume: 99, P: 1808-1815
Phase I and pharmacokinetic study of DACA (XR5000): a novel inhibitor of topoisomerase I and II

C J Twelves
C Gardner
N M Bleehen
ResearchOpen Access09 Jul 1999
British Journal of Cancer

Volume: 80, P: 1786-1791
A quasi affine transformation evolution algorithm with evolution matrix selection operation for parameter estimation of proton exchange membrane fuel cells

Mohammad Aljaidi
Pradeep Jangir
Laith Abualigah
ResearchOpen Access11 Jan 2025
Scientific Reports

Volume: 15, P: 1-37
A phase II study of weekly docetaxel and cisplatin plus oral tegafur/uracil and leucovorin as first-line chemotherapy in patients with locally advanced or metastatic gastric cancer

C-P Li
J-S Chen
Y Chao
ResearchOpen Access05 Oct 2010
British Journal of Cancer

Volume: 103, P: 1343-1348
A phase 1b/2, open-label, dose-escalation, and dose-confirmation study of eribulin mesilate in combination with capecitabine

Chris Twelves
Alan Anthoney
T. R. Jeffry Evans
ResearchOpen Access20 Feb 2019
British Journal of Cancer

Volume: 120, P: 579-586
Results of the phase IIa RADICAL trial of the FGFR inhibitor AZD4547 in endocrine resistant breast cancer

FGFR-1 upregulation has been associated with endocrine therapy resistance in breast cancer patients. Here the authors report the results of a phase IIa study to assess the safety and efficacy of AZD454, an inhibitor of FGFR-1, 2 and 3 receptor tyrosine kinases, in combination with anastrozole or letrozole, in estrogen receptor positive breast cancer patients.

R. C. Coombes
P. D. Badman
M. J. Seckl
ResearchOpen Access10 Jun 2022
Nature Communications

Volume: 13, P: 1-11
MHD instability dynamics and turbulence enhancement towards the plasma disruption at the HL-2A tokamak

Y. C. Li
M. Jiang
Yong Liu
ResearchOpen Access23 Mar 2023
Scientific Reports

Volume: 13, P: 1-14
Endogenous cortisol exerts antiemetic effect similar to that of exogenous corticosteroids

TJ Hursti
M Fredrikson
C Peterson
Research01 Jul 1993
British Journal of Cancer

Volume: 68, P: 112-114
High performance recycled CFRP composites based on reused carbon fabrics through sustainable mild solvolysis route

W. Ballout
N. Sallem-Idrissi
P. Van Velthem
ResearchOpen Access08 Apr 2022
Scientific Reports

Volume: 12, P: 1-15
Safety of UFT/LV and S-1 as adjuvant therapy for stage III colon cancer in phase III trial: ACTS-CC trial

I Mochizuki
H Takiuchi
K Sugihara
ResearchOpen Access13 Mar 2012
British Journal of Cancer

Volume: 106, P: 1268-1273
Oral cancer treatment: developments in chemotherapy and beyond

V J O'Neill
C J Twelves
ReviewsOpen Access21 Oct 2002
British Journal of Cancer

Volume: 87, P: 933-937
Capecitabine in combination with mitomycin C in patients with gastrointestinal cancer: results of an extended multicentre phase-I trial

R-D Hofheinz
J T Hartmann
A Hochhaus
ResearchOpen Access06 Jul 2004
British Journal of Cancer

Volume: 91, P: 834-838
Correlation of capecitabine-induced skin toxicity with treatment efficacy in patients with metastatic colorectal cancer: results from the German AIO KRK-0104 trial

S Stintzing
L Fischer von Weikersthal
V Heinemann
ResearchOpen Access12 Jul 2011
British Journal of Cancer

Volume: 105, P: 206-211
Continuous 5-fluorouracil in the treatment of breast cancer

DA Cameron
H Gabra
RCF Leonard
Research01 Jul 1994
British Journal of Cancer

Volume: 70, P: 120-124
Penetration of capecitabine and its metabolites into malignant and healthy tissues of patients with advanced breast cancer

R M Mader
C Schrolnberger
G G Steger
ResearchOpen Access04 Mar 2003
British Journal of Cancer

Volume: 88, P: 782-787
A phase I clinical and pharmacokinetic study of the new topoisomerase inhibitor GI147211 given as a 72-h continuous infusion

L Paz-Ares
R Kunka
P O'Dwyer
Research01 Nov 1998
British Journal of Cancer

Volume: 78, P: 1329-1336
Efficacy and tolerability of bevacizumab plus capecitabine as first-line therapy in patients with advanced hepatocellular carcinoma

C-H Hsu
T-S Yang
A-L Cheng
ResearchOpen Access16 Feb 2010
British Journal of Cancer

Volume: 102, P: 981-986
Adjuvant epirubicin followed by cyclophosphamide, methotrexate and fluorouracil (CMF) vs CMF in early breast cancer: results with over 7 years median follow-up from the randomised phase III NEAT/BR9601 trials

H M Earl
L Hiller
C J Poole
ResearchOpen Access11 Sept 2012
British Journal of Cancer

Volume: 107, P: 1257-1267
Potential for cost economies in guiding therapy in patients with metastatic breast cancer

JFR Robertson
DK Whynes
RW Blamey
Research01 Jul 1995
British Journal of Cancer

Volume: 72, P: 174-177
High-dose chemotherapy supported by peripheral blood progenitor cells in poor prognosis metastatic breast cancer--phase I/II study

DA Cameron
J Craig
W Miller
Research01 Dec 1996
British Journal of Cancer

Volume: 74, P: 2013-2017
Capecitabine and mitomycin C in patients with metastatic colorectal cancer resistant to fluorouracil and irinotecan

C Alliot
CorrespondenceOpen Access21 Feb 2006
British Journal of Cancer

Volume: 94, P: 935-936
Hepatitis B virus reactivation risk varies with different chemotherapy regimens commonly used in solid tumours

W H Y Ling
P P Soe
S-C Lee
ResearchOpen Access07 May 2013
British Journal of Cancer

Volume: 108, P: 1931-1935
A phase I trial of preoperative radiotherapy and capecitabine for locally advanced, potentially resectable rectal cancer

S Y K Ngan
M Michael
J R Zalcberg
ResearchOpen Access10 Aug 2004
British Journal of Cancer

Volume: 91, P: 1019-1024
Comparison of prognostic factors in patients in phase I trials of cytotoxic drugs vs new noncytotoxic agents

C Han
J P Braybrooke
D C Talbot
ResearchOpen Access30 Sept 2003
British Journal of Cancer

Volume: 89, P: 1166-1171
MTHFR-1298 A>C (rs1801131) is a predictor of survival in two cohorts of stage II/III colorectal cancer patients treated with adjuvant fluoropyrimidine chemotherapy with or without oxaliplatin

E Cecchin
G Perrone
G Toffoli
Research21 Oct 2014
The Pharmacogenomics Journal

Volume: 15, P: 219-225
Vinorelbine alternating oral and intravenous plus epirubicin in first-line therapy of metastatic breast cancer: results of a multicentre phase II study

D Serin
M Verrill
M Brandely
ResearchOpen Access31 May 2005
British Journal of Cancer

Volume: 92, P: 1989-1996
Capecitabine in hormone-resistant metastatic prostatic carcinoma – a phase II trial

R Morant
J Bernhard
H-P Schmid
ResearchOpen Access09 Mar 2004
British Journal of Cancer

Volume: 90, P: 1312-1317
Evaluation of rodent-only toxicology for early clinical trials with novel cancer therapeutics

D R Newell
S S Burtles
T A Connors
ResearchOpen Access15 Oct 1999
British Journal of Cancer

Volume: 81, P: 760-768
Preclinical cellular pharmacology of LY231514 (MTA): a comparison with methotrexate, LY309887 and raltitrexed for their effects on intracellular folate and nucleoside triphosphate pools in CCRF-CEM cells

VJ Chen
JR Bewley
JL Tonkinson
Research01 Jan 1998
British Journal of Cancer

Volume: 78, P: 27-34
Deleterious variants in LTBP4 are associated with severe pediatric sepsis

Yidi Qin
Kate F. Kernan
Hyun-Jung Park
ResearchOpen Access11 Oct 2025
Pediatric Research

P: 1-12
Abcc10 status affects mammary tumour growth, metastasis, and docetaxel treatment response

N Domanitskaya
J Wangari-Talbot
E Hopper-Borge
ResearchOpen Access17 Jun 2014
British Journal of Cancer

Volume: 111, P: 696-707
Phase I and pharmacokinetic study of XR11576, an oral topoisomerase I and II inhibitor, administered on days 1–5 of a 3-weekly cycle in patients with advanced solid tumours

M J A de Jonge
S Kaye
I Judson
ResearchOpen Access28 Sept 2004
British Journal of Cancer

Volume: 91, P: 1459-1465
Phase I and pharmacokinetic (PK) study of MAG-CPT (PNU 166148): a polymeric derivative of camptothecin (CPT)

D Bissett
J Cassidy
C Twelves
ResearchOpen Access08 Jun 2004
British Journal of Cancer

Volume: 91, P: 50-55
Modulation of 5-fluorouracil as adjuvant systemic chemotherapy in colorectal cancer: the IGCS-COL multicentre, randomised, phase III study

S De Placido
M Lopez
A R Bianco
ResearchOpen Access11 Oct 2005
British Journal of Cancer

Volume: 93, P: 896-904
Inequity in colorectal cancer treatment and outcomes: a population-based study

A-E Carsin
L Sharp
H Comber
ResearchOpen Access01 Jul 2008
British Journal of Cancer

Volume: 99, P: 266-274

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