Deep brain stimulation (DBS) of the subthalamic nucleus or globus pallidus internus can substantially improve appendicular motor symptoms of Parkinson disease (PD); however, the effect of DBS on axial motor signs—such as gait impairment, postural instability and postural abnormalities—is less clear. In this practically oriented Review, Fasanoet al. discuss the most important considerations to establish the reasons for gait problems in patients receiving DBS, and suggest how to manage axial disability in these patients.
- Alfonso Fasano
- Camila C. Aquino
- Bastiaan R. Bloem