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Microglia-neuron interaction at nodes of Ranvier depends on neuronal activity through potassium release and contributes to remyelination

Microglia are important for brain homeostasis and plasticity. The mechanisms underlying microglia-neuron interactions are still unclear. Here, the authors show that microglia preferentially interact with the nodes of Ranvier along axons. This interaction is modulated by neuronal activity and contributes to remyelination in mice.

R. Ronzano
T. Roux
A. Desmazières
ResearchOpen Access01 Sept 2021
Nature Communications

Volume: 12, P: 1-18
Facing the urgency of therapies for progressive MS — a Progressive MS Alliance proposal

In this article, members of the International Progressive MS Alliance discuss why experimental medicine trials are important for the development of treatments for progressive multiple sclerosis and set out their funding programme for such trials.

Fernando Dangond
Alexis Donnelly
Marco Salvetti
Reviews22 Jan 2021
Nature Reviews Neurology

Volume: 17, P: 185-192
Erratum: The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes

K Brookes
X Xu
P Asherson
Amendments and Corrections28 Nov 2006
Molecular Psychiatry

Volume: 11, P: 1139
The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes

K Brookes
X Xu
L Johansson
Research08 Aug 2006
Molecular Psychiatry

Volume: 11, P: 934-953
A high-density SNP linkage scan with 142 combined subtype ADHD sib pairs identifies linkage regions on chromosomes 9 and 16

P Asherson
K Zhou
S V Faraone
Research08 Jan 2008
Molecular Psychiatry

Volume: 13, P: 514-521

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Microglia-neuron interaction at nodes of Ranvier depends on neuronal activity through potassium release and contributes to remyelination

Facing the urgency of therapies for progressive MS — a Progressive MS Alliance proposal

Erratum: The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes

The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes

A high-density SNP linkage scan with 142 combined subtype ADHD sib pairs identifies linkage regions on chromosomes 9 and 16

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Microglia-neuron interaction at nodes of Ranvier depends on neuronal activity through potassium release and contributes to remyelination

Facing the urgency of therapies for progressive MS — a Progressive MS Alliance proposal

Erratum: The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes

The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes

A high-density SNP linkage scan with 142 combined subtype ADHD sib pairs identifies linkage regions on chromosomes 9 and 16

Search

Quick links