Nature Search

Blobby is a synaptic active zone assembly protein required for memory in Drosophila

The active zone is a brain signaling hub critical for synaptic information transfer and the encoding of behaviors. The authors identify Blobby as an assembly factor required for proper active zone nanoscale protein architecture and memory formation.

J. Lützkendorf
T. Matkovic-Rachid
S. J. Sigrist
ResearchOpen Access02 Jan 2025
Nature Communications

Volume: 16, P: 1-20
Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasis

Lysine hydroxylation of procollagen precursors by LH3 is required for collagen fibril crosslinking and stabilization. Here the authors show that the trafficking protein VIPAR is required for correct sorting of LH3 into post-Golgi collagen carriers and for correct collagen modification and structure.

Blerida Banushi
Federico Forneris
Paul Gissen
ResearchOpen Access20 Jul 2016
Nature Communications

Volume: 7, P: 1-14
Single-cell guided prenatal derivation of primary fetal epithelial organoids from human amniotic and tracheal fluids

The generation of primary organoids, from fetal fluid-derived epithelial stem or progenitor cells, offers the possibility of modeling different developing tissues during gestation, even beyond the limits of pregnancy termination.

Mattia Francesco Maria Gerli
Giuseppe Calà
Paolo De Coppi
ResearchOpen Access04 Mar 2024
Nature Medicine

Volume: 30, P: 875-887
Mutations in SLC39A14 disrupt manganese homeostasis and cause childhood-onset parkinsonism–dystonia

Karin Tuschl, Philippa Mills and colleagues report mutations in the manganese (Mn) transporter gene SLC39A14in childhood-onset parkinsonism-dystonia. Using functional recapitulation, the authors also show that slc39A14 loss-of-function in zebrafish can lead to Mn dysregulation and locomotor impairment.

Karin Tuschl
Esther Meyer
Stephen W. Wilson
ResearchOpen Access27 May 2016
Nature Communications

Volume: 7, P: 1-16
Author Correction: Single-cell guided prenatal derivation of primary fetal epithelial organoids from human amniotic and tracheal fluids

Mattia Francesco Maria Gerli
Giuseppe Calà
Paolo De Coppi
Amendments and CorrectionsOpen Access21 Jan 2025
Nature Medicine

Volume: 31, P: 699
Spring peaks and autumn troughs identified in peripheral inflammatory markers during the peripartum period

Hanna E. Henriksson
Richard A. White
Alkistis Skalkidou
ResearchOpen Access25 Oct 2019
Scientific Reports

Volume: 9, P: 1-13
Mutations in a new member of the chromodomain gene family cause CHARGE syndrome

Lisenka E L M Vissers
Conny M A van Ravenswaaij
Ad Geurts van Kessel
Research08 Aug 2004
Nature Genetics

Volume: 36, P: 955-957
Automated high-throughput mapping of promoter-enhancer interactions in zebrafish embryos

Methods for automated fluorescence imaging allow high-throughput examination of reporter expression patterns in zebrafish embryos. They are applied to mapping promoter-enhancer interactions in this organism.

Jochen Gehrig
Markus Reischl
Ferenc Müller
Research08 Nov 2009
Nature Methods

Volume: 6, P: 911-916
High tPA-expression in primary melanoma of the limb correlates with good prognosis

C M Ferrier
S Suciu
D J Ruiter
ResearchOpen Access24 Oct 2000
British Journal of Cancer

Volume: 83, P: 1351-1359
Trends of skin cancer in the Canton of Vaud, 1976-92

F Levi
S Franceschi
C La Vecchia
Research01 Oct 1995
British Journal of Cancer

Volume: 72, P: 1047-1053
Large molecular gas reservoirs in ancestors of Milky Way-mass galaxies nine billion years ago

Measurements of cold molecular gas from galaxies with stellar masses and star formation rates similar to those of the main progenitor of the Milky Way 8.5 billion years ago show similar physics of star formation to that seen now.

C. Papovich
I. Labbé
K.-V. Tran
Research19 Dec 2016
Nature Astronomy

Volume: 1, P: 1-6
A giant galaxy in the young Universe with a massive ring

A ring galaxy is found at a look-back time of 10.8 Gyr. The diffuse stellar light outside the star-forming ring, the ring’s radial velocity and a nearby intruder galaxy indicate that this is a collisional ring galaxy.

Tiantian Yuan
Ahmed Elagali
Sarah M. Sweet
Research25 May 2020
Nature Astronomy

Volume: 4, P: 957-964
Identification of a novel form of caspase-independent cell death triggered by BH3-mimetics in diffuse large B-cell lymphoma cell lines

Nahide Yildirim
Lakshmi Sarojam
Meike Vogler
ResearchOpen Access15 Apr 2024
Cell Death & Disease

Volume: 15, P: 1-10
DJ-1 interactions with α-synuclein attenuate aggregation and cellular toxicity in models of Parkinson’s disease

L Zondler
L Miller-Fleming
T F Outeiro
ResearchOpen Access24 Jul 2014
Cell Death & Disease

Volume: 5, P: e1350
Comparison of immunohistochemistry with immunoassay (ELISA) for the detection of components of the plasminogen activation system in human tumour tissue

C M Ferrier
H H de Witte
G N P van Muijen
ResearchOpen Access26 Feb 1999
British Journal of Cancer

Volume: 79, P: 1534-1541

Search

Blobby is a synaptic active zone assembly protein required for memory in Drosophila

Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasis

Single-cell guided prenatal derivation of primary fetal epithelial organoids from human amniotic and tracheal fluids

Mutations in SLC39A14 disrupt manganese homeostasis and cause childhood-onset parkinsonism–dystonia

Author Correction: Single-cell guided prenatal derivation of primary fetal epithelial organoids from human amniotic and tracheal fluids

Spring peaks and autumn troughs identified in peripheral inflammatory markers during the peripartum period

Mutations in a new member of the chromodomain gene family cause CHARGE syndrome

Automated high-throughput mapping of promoter-enhancer interactions in zebrafish embryos

High tPA-expression in primary melanoma of the limb correlates with good prognosis

Trends of skin cancer in the Canton of Vaud, 1976-92

Large molecular gas reservoirs in ancestors of Milky Way-mass galaxies nine billion years ago

A giant galaxy in the young Universe with a massive ring

Identification of a novel form of caspase-independent cell death triggered by BH3-mimetics in diffuse large B-cell lymphoma cell lines

DJ-1 interactions with α-synuclein attenuate aggregation and cellular toxicity in models of Parkinson’s disease

Comparison of immunohistochemistry with immunoassay (ELISA) for the detection of components of the plasminogen activation system in human tumour tissue

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