The'guardian of the genome', p53, is the best-known tumour-suppressor gene. Two other proteins — p63 and p73 — have similar sequences and properties to p53. But p53 is the only one to be induced by DNA damage. Or at least it was. A new study shows that, in fact, p73 is also induced by DNA damage via the non-receptor tyrosine kinase c-Abl.
