Nature Search

Unraveling sex differences in age-related hippocampal decline: differential mitochondrial dysfunction, Lonp1-dependent mitochondrial proteostasis and mtROS production in aged C57BL/6 mice

Karina A. Cicali
Claudia Jara
Cheril Tapia-Rojas
ResearchOpen Access30 Dec 2025
Cell Death & Disease

Volume: 17, P: 1-22
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

Paul R Burton
David G Clayton
Matthew A Brown
Research21 Oct 2007
Nature Genetics

Volume: 39, P: 1329-1337
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Tracking HPAIV H5 through a geographic survey of Antarctic seabird populations

Fabiola León
Céline Le Bohec
Juliana A. Vianna
ResearchOpen Access12 Aug 2025
Scientific Reports

Volume: 15, P: 1-6
The effect of blood flow modification on intra- and extracellular pH measured by ³¹P magnetic resonance spectroscopy in murine tumours

CL McCoy
CS Parkins
M Stubbs
Research01 Oct 1995
British Journal of Cancer

Volume: 72, P: 905-911
Antithrombin-III for the treatment of chemotherapy-induced organ dysfunction following bone marrow transplantation

JD Morris
RE Harris
CL Morris
Research01 Nov 1997
Bone Marrow Transplantation

Volume: 20, P: 871-878
Genetic variants associated with longitudinal changes in brain structure across the lifespan

Human brain structure changes throughout the lifespan. Brouwer et al. identified genetic variants that affect rates of brain growth and atrophy. The genes are linked to early brain development and neurodegeneration and suggest involvement of metabolic processes.

Rachel M. Brouwer
Marieke Klein
Hilleke E. Hulshoff Pol
Research05 Apr 2022
Nature Neuroscience

Volume: 25, P: 421-432
NAD⁺-boosting agent nicotinamide mononucleotide potently improves mitochondria stress response in Alzheimer’s disease via ATF4-dependent mitochondrial UPR

Xi Xiong
Jialong Hou
Chenglong Xie
ResearchOpen Access11 Oct 2024
Cell Death & Disease

Volume: 15, P: 1-21
Effectiveness of machine learning methods in detecting grooming: a systematic meta-analytic review

Marcelo Leiva-Bianchi
Nicolas Castillo
Francisco Ahumada-Méndez
ResearchOpen Access15 Mar 2025
Scientific Reports

Volume: 15, P: 1-17
Controlled induction of DNA double-strand breaks in the mouse liver induces features of tissue ageing

Accumulation of DNA damage is a hallmark of cellular ageing but cause and effect are unclear. Here White et al.induce clean DNA double-strand breaks in the liver of mice using a modified restriction enzyme and demonstrate that DNA damage alone is sufficient to recapitulate some aspects of tissue ageing.

Ryan R. White
Brandon Milholland
Jan Vijg
ResearchOpen Access10 Apr 2015
Nature Communications

Volume: 6, P: 1-11
β-sheet breaker peptide prevents Aβ-induced spatial memory impairments with partial reduction of amyloid deposits

M A Chacón
M I Barría
N C Inestrosa
Research20 Apr 2004
Molecular Psychiatry

Volume: 9, P: 953-961
Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1ΔE9 mouse model of Alzheimer's disease

E M Toledo
N C Inestrosa
Research21 Jul 2009
Molecular Psychiatry

Volume: 15, P: 272-285
The effects of atenolol and zofenopril on plasma atrial natriuretic peptide are due to their interactions with target organ damage of essential hypertensive patients

F Elijovich
CL Laffer
EL Schiffrin
Research01 May 1997
Journal of Human Hypertension

Volume: 11, P: 313-319
Flow cytometric analysis of neoplastic nodules and hepatocellular carcinomas induced by ciprofibrate in the rat

CL Goolsby
MS Rao
Reviews01 Jan 1996
British Journal of Cancer

Volume: 73, P: 197-202
A human prion protein peptide (PrP_59–91) protects against copper neurotoxicity

M A Chacón
M I Barría
N C Inestrosa
Research29 Sept 2003
Molecular Psychiatry

Volume: 8, P: 853-862
Lack of IRF-1 expression in acute promyelocytic leukemia and in a subset of acute myeloid leukemias with del(5)(q31)

WB Green
ML Slovak
CL Willman
Research02 Dec 1999
Leukemia

Volume: 13, P: 1960-1971
Tetrahydrohyperforin prevents cognitive deficit, Aβ deposition, tau phosphorylation and synaptotoxicity in the APPswe/PSEN1ΔE9 model of Alzheimer's disease: a possible effect on APP processing

N C Inestrosa
C Tapia-Rojas
L Varela-Nallar
ResearchOpen Access12 Jul 2011
Translational Psychiatry

Volume: 1, P: e20
Hyperforin prevents β-amyloid neurotoxicity and spatial memory impairments by disaggregation of Alzheimer's amyloid-β-deposits

M C Dinamarca
W Cerpa
N C Inestrosa
Research25 Jul 2006
Molecular Psychiatry

Volume: 11, P: 1032-1048
School behaviour and health status after central nervous system tumours in childhood

AW Glaser
NF Nik Abdul Rashid
DA Walker
Research01 Sept 1997
British Journal of Cancer

Volume: 76, P: 643-650
Creutzfeldt-Jakob disease and the eye. II. Ophthalmic and neuro-ophthalmic features

C J Lueck
G G McIlwaine
M Zeidler
Reviews01 May 2000
Eye

Volume: 14, P: 291-301
Emerging roles of Wnts in the adult nervous system

In addition to their roles in nervous system development, Wnts participate in synaptic maintenance and function and in adult neurogenesis. Here, Inestrosa and Arenas review the latest research on the functions of Wnt signalling in the adult nervous system and potential therapeutic implications.

Nibaldo C. Inestrosa
Ernest Arenas
Reviews16 Dec 2009
Nature Reviews Neuroscience

Volume: 11, P: 77-86
Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by β-amyloid fibrils

G V De Ferrari
M A Chacón
N C Inestrosa
Research27 Feb 2003
Molecular Psychiatry

Volume: 8, P: 195-208
Paternally inherited markers in bovine hybrid populations

E L C Verkaar
H Vervaecke
J A Lenstra
Research24 Sept 2003
Heredity

Volume: 91, P: 565-569
Assessing cross-species transmission of hemoplasmas at the wild-domestic felid interface in Chile using genetic and landscape variables analysis

I. Sacristán
F. Acuña
C. Napolitano
ResearchOpen Access14 Nov 2019
Scientific Reports

Volume: 9, P: 1-14

Search

Unraveling sex differences in age-related hippocampal decline: differential mitochondrial dysfunction, Lonp1-dependent mitochondrial proteostasis and mtROS production in aged C57BL/6 mice

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

A second update on mapping the human genetic architecture of COVID-19

Tracking HPAIV H5 through a geographic survey of Antarctic seabird populations

The effect of blood flow modification on intra- and extracellular pH measured by ³¹P magnetic resonance spectroscopy in murine tumours

Antithrombin-III for the treatment of chemotherapy-induced organ dysfunction following bone marrow transplantation

Genetic variants associated with longitudinal changes in brain structure across the lifespan

NAD⁺-boosting agent nicotinamide mononucleotide potently improves mitochondria stress response in Alzheimer’s disease via ATF4-dependent mitochondrial UPR

Effectiveness of machine learning methods in detecting grooming: a systematic meta-analytic review

Controlled induction of DNA double-strand breaks in the mouse liver induces features of tissue ageing

β-sheet breaker peptide prevents Aβ-induced spatial memory impairments with partial reduction of amyloid deposits

Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1ΔE9 mouse model of Alzheimer's disease

The effects of atenolol and zofenopril on plasma atrial natriuretic peptide are due to their interactions with target organ damage of essential hypertensive patients

Flow cytometric analysis of neoplastic nodules and hepatocellular carcinomas induced by ciprofibrate in the rat

A human prion protein peptide (PrP_59–91) protects against copper neurotoxicity

Lack of IRF-1 expression in acute promyelocytic leukemia and in a subset of acute myeloid leukemias with del(5)(q31)

Tetrahydrohyperforin prevents cognitive deficit, Aβ deposition, tau phosphorylation and synaptotoxicity in the APPswe/PSEN1ΔE9 model of Alzheimer's disease: a possible effect on APP processing

Hyperforin prevents β-amyloid neurotoxicity and spatial memory impairments by disaggregation of Alzheimer's amyloid-β-deposits

School behaviour and health status after central nervous system tumours in childhood

Creutzfeldt-Jakob disease and the eye. II. Ophthalmic and neuro-ophthalmic features

Emerging roles of Wnts in the adult nervous system

Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by β-amyloid fibrils

Paternally inherited markers in bovine hybrid populations

Assessing cross-species transmission of hemoplasmas at the wild-domestic felid interface in Chile using genetic and landscape variables analysis

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