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Advanced filters: Author: Caitlin Drescher Clear advanced filters

  • Cuprizone causes demyelination and oligodendrocyte death in mice. Cuprizone lesions resemble a particular form of white-matter lesions that is seen in multiple sclerosis. This study reports that infiltrating neutrophils expressing the chemokine receptor CXCR2 contribute to oligodendrocyte death in the cuprizone model of demyelination.

    • LiPing Liu
    • Abdelmadjid Belkadi
    • Richard M Ransohoff
    Research
    Nature Neuroscience
    Volume: 13, P: 319-326