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Showing 1–3 of 3 results
Advanced filters: Author: Caitlin E. McDonough-Goldstein Clear advanced filters

  • A comparative analysis of morphological data across 149 species of Drosophilidae shows that sperm length in males has co-evolved with the length of the sperm-storage organ in females. Combining a genome-wide association study of these traits in Drosophila melanogaster with molecular evolutionary analyses of the genomes of 15 Drosophila species, the authors find that the genetic architecture underlying sperm length is associated with indirect genetic benefits in females, providing support for the ‘good genes’ hypothesis.

    • Zeeshan A. Syed
    • R. Antonio Gomez
    • Scott Pitnick
    Research
    Nature Ecology & Evolution
    Volume: 9, P: 336-348

  • Authors show that a common SNP upregulates endometrial Wnt4 expression and proimplantation genes in mouse proestrus and estrus. They suggest that this increases uterine permissiveness to embryo invasion, while decreasing resistance to invasion in reproductive cancers and endometriosis.

    • Mihaela Pavličev
    • Caitlin E. McDonough-Goldstein
    • Louis Muglia
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14