Mice with myeloid-specific loss of the transcription factor, Stat4, exhibit stronger long-term synaptic plasticity than control animals when given a high-fat, high-cholesterol diet, suggesting that suppressing Stat4 activation may be a useful strategy for protecting against the inflammatory effects of a Western diet.
- Xiao-lei Zhang
- Callie M. Hollander
- Patric K. Stanton
