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A polarized FGF8 source specifies frontotemporal signatures in spatially oriented cell populations of cortical assembloids

Cortical development is influenced by morphogen gradients. To mimic patterning events during brain development, polarized cortical assembloids are generated with the help of a localized FGF8 source.

Camilla Bosone
Davide Castaldi
Jürgen Arthur Knoblich
ResearchOpen Access18 Sept 2024
Nature Methods

Volume: 21, P: 2147-2159

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A polarized FGF8 source specifies frontotemporal signatures in spatially oriented cell populations of cortical assembloids

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