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Showing 1–2 of 2 results
Advanced filters: Author: Canglin Yao Clear advanced filters

  • DNA N6-adenine methylation (6 mA) plays a crucial role in epigenetic regulation in eukaryotes. Here, the authors determined nine crystal structures of the ciliates 6 mA methyltransferase complexes, providing the molecular basis for understanding the functions of 6 mA.

    • Jiyun Chen
    • Rong Hu
    • Liang Liu
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-15

  • A soluble bacterial transhydrogenase from Escherichia coli (EcSTH) was validated as a genetically encoded tool to induce NADH reductive stress in mammalian cells revealing unique transcriptional and metabolic signatures.

    • Xingxiu Pan
    • Mina L. Heacock
    • Valentin Cracan
    Research
    Nature Chemical Biology
    Volume: 20, P: 594-604