The asymmetric distribution of lipopolysaccharide (LPS) on the surface of the bacterial outer membrane is essential and crucial for antibiotic resistance. Here, authors characterize the LPS translocon holo-complex, LptDEMY, uncovering conformational translocon state transitions that might explain how LPS is assembled at the outer membrane surface.
- Haoxiang Chen
- Axel Siroy
- Raffaele Ieva
