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ARMH2 is a cytosolic component of CatSper crucial for sperm function

ARMH2 is identified as a previously unknown cytosolic component of the sperm-specific CatSper channel, critical for its normal assembly and pH/calcium sensitivity. Loss of ARMH2 impairs sperm hyperactivation and causes severe subfertility.

Qingqing Zhao
Shiyi Lin
Jianping Wu
ResearchOpen Access21 Nov 2025
Nature Communications

Volume: 16, P: 1-15
Diminishing benefits of urban living for children and adolescents’ growth and development

The advantage of living in cities compared with rural areas with respect to height and BMI in children and adolescents has generally become smaller globally from 1990 to 2020, except in sub-Saharan Africa.

Anu Mishra
Bin Zhou
Majid Ezzati
ResearchOpen Access29 Mar 2023
Nature

Volume: 615, P: 874-883
Rising rural body-mass index is the main driver of the global obesity epidemic in adults

Contrary to the view that urbanization is a major driver of the global rise in obesity, the global increase in body-mass index is shown to be mostly due to increases in the body-mass indexes of rural populations.

Honor Bixby
James Bentham
Majid Ezzati
ResearchOpen Access08 May 2019
Nature

Volume: 569, P: 260-264
Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

Mammalian genomes are scattered with repetitive sequences, but their biology remains largely elusive. Here, the authors show that transcription can initiate from short tandem repetitive sequences, and that genetic variants linked to human diseases are preferentially found at repeats with high transcription initiation level.

Mathys Grapotte
Manu Saraswat
Charles-Henri Lecellier
ResearchOpen Access02 Jun 2021
Nature Communications

Volume: 12, P: 1-18
Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

Mathys Grapotte
Manu Saraswat
Charles-Henri Lecellier
Amendments and CorrectionsOpen Access01 Mar 2022
Nature Communications

Volume: 13, P: 1

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ARMH2 is a cytosolic component of CatSper crucial for sperm function

Diminishing benefits of urban living for children and adolescents’ growth and development

Rising rural body-mass index is the main driver of the global obesity epidemic in adults

Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

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