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Advanced filters: Author: Carlos Marcuello Clear advanced filters

Two-dimensional HRS condensates drive the assembly of flat clathrin lattices on endosomes

The ESCRT-protein HRS undergoes two-dimensional phase separation on endosomal membranes to form gel-like condensates that recruit clathrin into multilayered, flat coats. Cholesterol enhances this process and drives stable cargo-sorting microdomains

Markku Hakala
Satish Babu Moparthi
Aurélien Roux
ResearchOpen Access12 May 2026
Nature Communications

P: 1-23
UGT1A and TYMS genetic variants predict toxicity and response of colorectal cancer patients treated with first-line irinotecan and fluorouracil combination therapy

E Martinez-Balibrea
A Abad
V Moreno
ResearchOpen Access13 Jul 2010
British Journal of Cancer

Volume: 103, P: 581-589
The FAD synthetase from the human pathogen Streptococcus pneumoniae: a bifunctional enzyme exhibiting activity-dependent redox requirements

María Sebastián
Erandi Lira-Navarrete
Marta Martínez-Júlvez
ResearchOpen Access08 Aug 2017
Scientific Reports

Volume: 7, P: 1-15

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Two-dimensional HRS condensates drive the assembly of flat clathrin lattices on endosomes

UGT1A and TYMS genetic variants predict toxicity and response of colorectal cancer patients treated with first-line irinotecan and fluorouracil combination therapy

The FAD synthetase from the human pathogen Streptococcus pneumoniae: a bifunctional enzyme exhibiting activity-dependent redox requirements

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