Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–12 of 12 results
Advanced filters: Author: Carmelo Quarta Clear advanced filters

  • Whether and how hypothalamic neurons can lose or change their identity in adulthood has remained elusive. Here, the authors show that mature pro-opiomelanocortin (Pomc) neurons contain invisible ‘Ghost’ subsets with atypical identities that are recruited in response to obesogenic stimuli.

    • Stéphane Leon
    • Vincent Simon
    • Carmelo Quarta
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14

  • Hypothalamic melanocortin neurons control energy homoeostasis by modulating appetite. Here, the authors reveal a role for the transcription factor Tbx3 as a regulator of the peptidergic identity and function of immature and mature mouse melanocortin neurons.

    • Carmelo Quarta
    • Alexandre Fisette
    • Matthias H. Tschöp
    Research
    Nature Metabolism
    Volume: 1, P: 222-235

  • Histone deacetylases (HDACs) regulate energy metabolism in peripheral tissues, but whether HDACs expressed in the brain influence systemic metabolism is unknown. Here the authors show that hypothalamic HDAC5 expression is affected by the diet and HDAC5 regulates leptin sensitivity by deacetylating STAT3.

    • Dhiraj G. Kabra
    • Katrin Pfuhlmann
    • Paul T. Pfluger
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-12

  • Tobacco smoking and cold exposure are environmental modulators of human energy metabolism suppressing appetite and increasing energy expenditure, respectively. Here, the authors develop a novel pharmacological strategy in which they simultaneously mimic the metabolic benefits of both phenomena through small-molecule combination therapy, and show that this treatment improves metabolic health of obese mice.

    • Christoffer Clemmensen
    • Sigrid Jall
    • Matthias H. Tschöp
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-13

  • This study shows that activation of cannabinoid type-1 (CB1) receptors in the olfactory bulb increases odor detection and food intake in hungry mice. The authors show that this function is mediated by CB1-dependent attenuation of excitatory corticofugal synaptic transmission onto inhibitory granule cells and disinhibition of mitral cells in the main olfactory bulb.

    • Edgar Soria-Gómez
    • Luigi Bellocchio
    • Giovanni Marsicano
    Research
    Nature Neuroscience
    Volume: 17, P: 407-415

  • In metabolic studies using rodents, body weight and food intake measurements seem easy to obtain, but several potential pitfalls can lead to erroneous data generation and interpretation. This Comment raises awareness of key conceptual and technical aspects that can increase the quality and reproducibility of this type of data.

    • Camille Allard
    • Philippe Zizzari
    • Daniela Cota
    Comments & Opinion
    Nature Metabolism
    Volume: 4, P: 1424-1426

  • This Review critically examines the evidence base in precision nutrition research, discusses the challenges in translating short-term studies into long-term clinical effectiveness and highlights the many opportunities that lie ahead.

    • Marta Guasch-Ferré
    • Clemens Wittenbecher
    • Jordi Merino
    Reviews
    Nature Medicine
    Volume: 31, P: 1444-1453