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Advanced filters: Author: Carolina M. Alvadia Clear advanced filters

Structural basis for the activation of the lipid scramblase TMEM16F

TMEM16F is a dual ion channel and lipid scramblase that is involved in blood coagulation and cell fusion. Here, authors elucidate how the protein is activated by Ca2+ to accomplish both functions in a single protein conformation.

Melanie Arndt
Carolina Alvadia
Raimund Dutzler
ResearchOpen Access05 Nov 2022
Nature Communications

Volume: 13, P: 1-17
The crystal structure of the regulatory domain of the human sodium-driven chloride/bicarbonate exchanger

Carolina M. Alvadia
Theis Sommer
J. Preben Morth
ResearchOpen Access21 Sept 2017
Scientific Reports

Volume: 7, P: 1-12

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Structural basis for the activation of the lipid scramblase TMEM16F

The crystal structure of the regulatory domain of the human sodium-driven chloride/bicarbonate exchanger

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