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Showing 1–21 of 21 results
Advanced filters: Author: Caroline Seydel Clear advanced filters

  • Nature Biotechnology’s annual survey highlights university startups that are, among other things, rethinking how to deliver gene-editing therapy and tackling various metabolic conditions, immune disorders and cancer with microbiome treatments or immunotherapy. Michael Eisenstein, Ken Garber, Esther Landhuis, Caroline Seydel and Laura DeFrancesco report.

    • Michael Eisenstein
    • Ken Garber
    • Laura DeFrancesco
    News
    Nature Biotechnology
    Volume: 39, P: 1036-1047

  • Our annual survey highlights startups tackling intractable viruses with new vaccine design, engineering a reliable source of platelets, universalizing cell therapies, improving cancer screening, developing RNA-editing platforms and targeting protein–RNA interactions. Michael Eisenstein, Ken Garber, Caroline Seydel and Laura DeFrancesco report.

    • Michael Eisenstein
    • Ken Garber
    • Laura DeFrancesco
    Special Features
    Nature Biotechnology
    Volume: 38, P: 546-554

  • Moving beyond viral vectors and lipid nanoparticles, Spotlight is conjugating Cas proteins to agents that will home endonucleases and their guide RNAs to targets in vivo.

    • Caroline Seydel
    News
    Nature Biotechnology

  • Advances in label-free microscopy allow researchers to visualize the invisible in complex biological systems, even living animals, from whole organs down to the tiniest peptides.

    • Caroline Seydel
    Special Features
    Nature Methods
    Volume: 22, P: 652-657

  • Precision genetic methods are enabling more efficient, environmentally friendly pest control methods for agricultural use as well as stopping the spread of disease.

    • Caroline Seydel
    News
    Nature Biotechnology
    Volume: 42, P: 1633-1636

  • The global imaging community is pursuing innovative approaches to achieve more equitable access to instruments and expertise.

    • Caroline Seydel
    Special Features
    Nature Methods
    Volume: 21, P: 1581-1586

  • For most of its history, biomedical research and clinical testing has neglected over half of the world’s population. Finally, researchers and funders are starting to recognize the importance of sex differences.

    • Caroline Seydel
    News
    Nature Biotechnology
    Volume: 39, P: 260-265

  • As new technologies hit the market, synthetic DNA is available faster and cheaper than ever before. Regulators are preparing to step in to limit opportunities for misuse.

    • Caroline Seydel
    News
    Nature Biotechnology
    Volume: 41, P: 1504-1509

  • Making biological research more sustainable requires an accurate assessment of its environmental impact, both at the bench and on the computer.

    • Caroline Seydel
    Special Features
    Nature Methods
    Volume: 20, P: 1449-1453

  • From made-to-order genetic therapies to model organisms engineered to be ‘patient avatars’, the technology exists right now to save patients with rare diseases.

    • Caroline Seydel
    News
    Nature Biotechnology
    Volume: 41, P: 441-446

  • As new technology enables researchers to find and characterize less-common post-translational modifications that drive gene expression and cellular metabolism, the movement to catalog the entire human proteome gains momentum

    • Caroline Seydel
    Special Features
    Nature Methods
    Volume: 19, P: 1036-1040

  • Whole-genome sequencing may be the fastest way to diagnose rare complex diseases, but should it be incorporated into healthy newborn screening?

    • Caroline Seydel
    News
    Nature Biotechnology
    Volume: 40, P: 636-640

  • An array of new techniques allow researchers to catalog the chemical contents of a single cell, or even a single organelle.

    • Caroline Seydel
    Special Features
    Nature Methods
    Volume: 18, P: 1452-1456

  • The University of Washington’s Institute for Protein Design has become a hub to galvanize de novo protein engineering, citizen science and much more since its founding in 2012.

    • Caroline Seydel
    News
    Nature Biotechnology
    Volume: 38, P: 779-784