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Showing 1–3 of 3 results
Advanced filters: Author: Carsten Wloka Clear advanced filters

  • Biological nanopore–based protein sequencing and recognition is challenging due to the folded structure or non-uniform charge of peptides. Here the authors show that engineered FraC nanopores can overcome these problems and recognize biomarkers in the form of oligopeptides, polypeptides and folded proteins.

    • Gang Huang
    • Kherim Willems
    • Giovanni Maglia
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-11

  • Protein nanopores are emerging as sensors for a variety of biomolecules. Here the authors develop a nanopore based on the bacterial toxin ClyA, in conjunction with binding proteins for glucose and asparagine, to detect these biomolecules simultaneously from a variety of unprocessed, diluted body fluids.

    • Nicole Stéphanie Galenkamp
    • Misha Soskine
    • Giovanni Maglia
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-8

  • In budding yeast, septin filaments adopt an hourglass structure at the bud neck that is remodelled into a double ring. Ong et al.reveal in fine detail the dynamic reorganization of septin filaments within these structures through the cell cycle using platinum-replica electron microscopy.

    • Katy Ong
    • Carsten Wloka
    • Erfei Bi
    Research
    Nature Communications
    Volume: 5, P: 1-10