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Showing 1–2 of 2 results
Advanced filters: Author: Cathy J. Spangler Clear advanced filters
  • Spangler et al. used a substrate inhibitor covalent conjugate strategy to solve cryo-EM structures of nucleosomes in complex with the lysine demethylase KDM2, which demonstrates that KDM2A, but not its closely related paralog, KDM2B, anchors to the acidic patch to direct histone H3K36-specific demethylation.

    • Cathy J. Spangler
    • Aleksandra Skrajna
    • Robert K. McGinty
    Research
    Nature Chemical Biology
    Volume: 19, P: 624-632
  • Cryo-electron microscopy analyses of calcium-permeable AMPA receptors from rat brain show that they are composed primarily of GluA1 and GluA4 subunits, and biochemical studies show that noelin promotes inter-receptor interactions without modulating receptor function.

    • Chengli Fang
    • Cathy J. Spangler
    • Eric Gouaux
    ResearchOpen Access
    Nature
    Volume: 645, P: 526-534