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Advanced filters: Author: Chanikarn Srinark Clear advanced filters

  • Prions are infectious agents that initiate transmissible spongiform encephalopathies. The study demonstrates that Prion proteins lower cellular oxidative stress via GPX8, remodel membrane lipids, and together with RAC3, sensitize cells to ferroptotic death, highlighting new therapeutic targets in prion diseases.

    • Hao Peng
    • Susanne Pfeiffer
    • Joel A. Schick
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-17