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Advanced filters: Author: Chanly Chheang Clear advanced filters

Piezo1 expression in neutrophils regulates shear-induced NETosis

Neutrophils undergo shear stress in the circulation and mechano-sensing is known to impact neutrophil biology. Here the authors show that activation of Piezo1 by shear stress triggers a sequence of cellular events leading to NETosis.

Sara Baratchi
Habiba Danish
Karlheinz Peter
ResearchOpen Access22 Aug 2024
Nature Communications

Volume: 15, P: 1-14
Characterization of the Src-regulated kinome identifies SGK1 as a key mediator of Src-induced transformation

The systemic understanding of oncogenic kinase signalling is still limited. Here, the authors combine chemical proteomics with functional screens to assess the impact of oncogenic Src on the expressed kinome and identify SGK1 as a critical mediator of Src-induced cell transformation.

Xiuquan Ma
Luxi Zhang
Roger J. Daly
ResearchOpen Access17 Jan 2019
Nature Communications

Volume: 10, P: 1-16
Investigating the effects of low intensity visible light on human keratinocytes using a customized LED exposure system

Emily Sutterby
Chanly Chheang
Elena Pirogova
ResearchOpen Access07 Nov 2022
Scientific Reports

Volume: 12, P: 1-11

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