Nature Search

Delayed gut microbiota maturation in the first year of life is a hallmark of pediatric allergic disease

Here, using participants in the CHILD birth cohort, the authors reveal that impaired 1-year microbiota maturation may be universal to 5-year pediatric allergies, mediated by functional and metabolic imbalances of compromised mucous integrity, elevated oxidative activity, decreased fermentation, and elevated trace amines.

Courtney Hoskinson
Darlene L. Y. Dai
Stuart E. Turvey
ResearchOpen Access29 Aug 2023
Nature Communications

Volume: 14, P: 1-14
MAGinator enables accurate profiling of de novo MAGs with strain-level phylogenies

Metagenomic sequencing enhances microbiome analysis and understanding of microbial relationships but lacks tools for subspecies-level resolution. Here, authors present MAGinator, a tool that enables accurate profiling of microbiomes with strain-level information.

Trine Zachariasen
Jakob Russel
Jonathan Thorsen
ResearchOpen Access09 Jul 2024
Nature Communications

Volume: 15, P: 1-10
MHC variation sculpts individualized microbial communities that control susceptibility to enteric infection

Composition of the gut microbiota is regulated by IgA antibodies which are produced under the control of MHCII-restricted B cells. Here the authors show that MHCII polymorphisms sculpt bacterial composition of the gut, which influences a host’s susceptibility to enteric Salmonellainfection.

Jason L. Kubinak
W. Zac Stephens
June L. Round
ResearchOpen Access23 Oct 2015
Nature Communications

Volume: 6, P: 1-13
Diversity and dynamism of IgA−microbiota interactions

Intestinal IgA is important for regulating the commensal microbiota and for preventing harmful pathogens from colonizing the intestine. In this Review, Huus, Petersen and Finlay consider the host, bacterial and environmental factors that shape IgA–microbiota interactions in the intestine.

Kelsey E. Huus
Charisse Petersen
B. Brett Finlay
Reviews10 Feb 2021
Nature Reviews Immunology

Volume: 21, P: 514-525
Longitudinal body mass index trajectories at preschool age: children with rapid growth have differential composition of the gut microbiota in the first year of life

Myrtha E. Reyna
Charisse Petersen
Padmaja Subbarao
ResearchOpen Access15 Apr 2022
International Journal of Obesity

Volume: 46, P: 1351-1358
Early prediction of pediatric asthma in the Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort using machine learning

Ping He
Theo J. Moraes
Lauren Erdman
ResearchOpen Access11 Jan 2024
Pediatric Research

Volume: 95, P: 1818-1825

Search

Filter By:

Delayed gut microbiota maturation in the first year of life is a hallmark of pediatric allergic disease

MAGinator enables accurate profiling of de novo MAGs with strain-level phylogenies

MHC variation sculpts individualized microbial communities that control susceptibility to enteric infection

Diversity and dynamism of IgA−microbiota interactions

Longitudinal body mass index trajectories at preschool age: children with rapid growth have differential composition of the gut microbiota in the first year of life

Early prediction of pediatric asthma in the Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort using machine learning

Search

Quick links