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Showing 1–3 of 3 results
Advanced filters: Author: Charles Fouillade Clear advanced filters

  • Radiation damages the healthy lung and triggers severe side effects. Here the authors provide a single cell atlas of the lung responses to radiation injury to explore the spatio-temporal dynamics of the mechanisms leading to radio-induced pulmonary fibrosis.

    • Sandra Curras-Alonso
    • Juliette Soulier
    • Charles Fouillade
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-16

  • Lamin A/C protects alveolar macrophages against nuclear envelope rupture and DNA damage, but it erodes during aging. Lack of lamin A/C leads to senescence and an aging signature, resulting in vulnerability to influenza virus and lung cancer growth.

    • Nilushi S. De Silva
    • Johan Siewiera
    • Nicolas Manel
    Research
    Nature Aging
    Volume: 3, P: 1251-1268

  • ComSeg is a cell segmentation algorithm for image-based spatial transcriptomics. ComSeg operates directly on single RNA positions, leveraging nuclei positions, and is applicable to complex tissues with arbitrary cell shapes.

    • Thomas Defard
    • Hugo Laporte
    • Thomas Walter
    ResearchOpen Access
    Communications Biology
    Volume: 7, P: 1-13