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Showing 1–3 of 3 results
Advanced filters: Author: Charles P. Rabolli Clear advanced filters

  • The adult mammalian heart has a limited cardiomyogenic capacity. Here the authors show that intensive exercise leads to a 4.6-fold increase in murine cardiomyocyte proliferation requiring the expression of miR-222, and that exercise induces an extended cardiomyogenic response in the murine heart after infarction.

    • Ana Vujic
    • Carolin Lerchenmüller
    • Anthony Rosenzweig
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-9

  • This study highlights the role of YTHDF2, a protein that recognizes m6A-modified RNA, in determining muscle size. The authors show a post-transcriptional mechanism regulating muscle catabolism and growth, prompting interest to address muscle wasting.

    • Christopher J. Gilbert
    • Charles P. Rabolli
    • Federica Accornero
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-18