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Showing 1–8 of 8 results
Advanced filters: Author: Chayasith Uttamapinant Clear advanced filters

  • The production of high-value chemicals can involve energy-intensive processes, necessitating sustainable production strategies. Here the authors present a circular bioeconomy approach, upcycling plastic waste through microbial conversion into levodopa, a medicine for Parkinson’s disease.

    • Benjamin Royer
    • Yuta Era
    • Stephen Wallace
    ResearchOpen Access
    Nature Sustainability
    P: 1-8

  • The specific high-sensitivity enzymatic reporter unlocking (SHERLOCK) assay detected severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA with high sensitivity and specificity in hundreds of nasopharyngeal and throat swab samples collected at Siriraj Hospital in Thailand.

    • Maturada Patchsung
    • Krittapas Jantarug
    • Chayasith Uttamapinant
    Research
    Nature Biomedical Engineering
    Volume: 4, P: 1140-1149

  • High-fidelity convergent total synthesis is used to produce Escherichia coli with a 61-codon synthetic genome that uses 59 codons to encode all of the canonical amino acids.

    • Julius Fredens
    • Kaihang Wang
    • Jason W. Chin
    Research
    Nature
    Volume: 569, P: 514-518

  • Many alternative ORFs are co-encoded with characterized proteins, but their function is often not understood. Here, the authors discover that ribosomal protein L36 is co-encoded with alternative protein, which they identify as an upstream regulator of PI3K-AKT-mTOR signaling.

    • Xiongwen Cao
    • Alexandra Khitun
    • Sarah A. Slavoff
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15

  • Upon ligand binding epidermal growth factor receptor (EGFR) dimerizes and activates its intrinsic kinase to auto-phosphorylate EGFR. Here, the authors engineer and image a FRET-based conformational EGFR indicator which reveals that activation loop phosphorylation induces a catalytically active conformation in EGFR monomers.

    • Martin Baumdick
    • Márton Gelléri
    • Philippe I. H. Bastiaens
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-13