Nature Search

S100A12 triggers NETosis to aggravate myocardial infarction injury via the Annexin A5-calcium axis

Neutrophil extracellular traps (NETs) contribute to heart damage after acute myocardial infarction (AMI). Here, the authors show that S100A12 promotes NETs formation and worsens injury, whereas blocking its interaction with ANXA5 reduces damage, suggesting a new therapeutic target for AMI.

Xi Zhang
Haixu Song
Yaling Han
ResearchOpen Access18 Feb 2025
Nature Communications

Volume: 16, P: 1-16
Association of hemoglobin with decreased prevalence of diabetic retinopathy among Tibetan male patients

Weijing Yin
Yan Ye
Chenghui Zhang
ResearchOpen Access17 Apr 2025
Scientific Reports

Volume: 15, P: 1-8
Single-cell transcriptomics in MI identify Slc25a4 as a new modulator of mitochondrial malfunction and apoptosis-associated cardiomyocyte subcluster

Ting Zhou
Jing Pan
Yaling Han
ResearchOpen Access23 Apr 2024
Scientific Reports

Volume: 14, P: 1-17
Genome sequence and genetic diversity of the common carp, Cyprinus carpio

Xiaowen Sun and colleagues report the whole-genome sequencing of the common carp, Cyprinus carpio. They also resequenced 33 representative accessions from a worldwide collection and provide insights into population structure and evolution.

Peng Xu
Xiaofeng Zhang
Xiaowen Sun
ResearchOpen Access21 Sept 2014
Nature Genetics

Volume: 46, P: 1212-1219
Efficient oxygen evolution electrocatalysis in acid by a perovskite with face-sharing IrO₆ octahedral dimers

While splitting water may provide a renewable source of carbon-neutral energy, the water oxidation half-reaction is sluggish and the materials needed show poor stability. Here, authors demonstrate an unusual iridium-based oxide to perform high-efficiency oxygen evolution in acid with good stability.

Lan Yang
Guangtao Yu
Xiaoxin Zou
ResearchOpen Access07 Dec 2018
Nature Communications

Volume: 9, P: 1-9
Potential therapeutic targets for COVID-19 complicated with pulmonary hypertension: a bioinformatics and early validation study

Qingbin Hou
Jinping Jiang
Yaling Han
ResearchOpen Access23 Apr 2024
Scientific Reports

Volume: 14, P: 1-19
FGF21-FGFR1 controls mitochondrial homeostasis in cardiomyocytes by modulating the degradation of OPA1

Bing Yan
Zhu Mei
Yaling Han
ResearchOpen Access08 May 2023
Cell Death & Disease

Volume: 14, P: 1-15
Tumor-derived HMGB1 induces CD62L^dim neutrophil polarization and promotes lung metastasis in triple-negative breast cancer

Zhen Wang
Chenghui Yang
Jian Huang
ResearchOpen Access17 Sept 2020
Oncogenesis

Volume: 9, P: 1-17
Identification of critical endoplasmic reticulum stress-related genes in advanced atherosclerotic plaque

Ning Zhao
Dan Liu
Yaling Han
ResearchOpen Access15 Jan 2025
Scientific Reports

Volume: 15, P: 1-23
Recurrent RNA edits in human preimplantation potentially enhance maternal mRNA clearance

An integrated analysis of RNA editing events in human embryo development suggests that recurrent RNA edits might enhance maternal mRNA clearance.

Yang Ding
Yang Zheng
Xiaochen Bo
ResearchOpen Access21 Dec 2022
Communications Biology

Volume: 5, P: 1-13
Identification of hub modules and therapeutic targets associated with CD8⁺T-cells in HF and their pan-cancer analysis

Jing Pan
Ting Zhou
Yaling Han
ResearchOpen Access13 Aug 2024
Scientific Reports

Volume: 14, P: 1-19
Unraveling shared molecular signatures and potential therapeutic targets linking psoriasis and acute myocardial infarction

Zheming Yang
Jiayin Li
Yaling Han
ResearchOpen Access16 Jul 2024
Scientific Reports

Volume: 14, P: 1-17
Assessing generalisability of deep learning-based polyp detection and segmentation methods through a computer vision challenge

Sharib Ali
Noha Ghatwary
James E. East
ResearchOpen Access23 Jan 2024
Scientific Reports

Volume: 14, P: 1-16
Unraveling the molecular links between benzopyrene exposure, NASH, and HCC: an integrated bioinformatics and experimental study

Zheming Yang
Jiayin Li
Yaling Han
ResearchOpen Access22 Nov 2023
Scientific Reports

Volume: 13, P: 1-16
Bioinformatics analyses of potentially common pathogenic networks for primary Sjögren’s syndrome complicated with acute myocardial infarction

Qingbin Hou
Jinping Jiang
Yaling Han
ResearchOpen Access06 Nov 2023
Scientific Reports

Volume: 13, P: 1-15
The CREG1-FBXO27-LAMP2 axis alleviates diabetic cardiomyopathy by promoting autophagy in cardiomyocytes

Dan Liu
Ruinan Xing
Yaling Han
ResearchOpen Access01 Sept 2023
Experimental & Molecular Medicine

Volume: 55, P: 2025-2038
Exploring shared therapeutic targets in diabetic cardiomyopathy and diabetic foot ulcers through bioinformatics analysis

Hanlin Wu
Zheming Yang
Yaling Han
ResearchOpen Access02 Jan 2024
Scientific Reports

Volume: 14, P: 1-15
GCN5-mediated regulation of pathological cardiac hypertrophy via activation of the TAK1-JNK/p38 signaling pathway

Jia Li
Chenghui Yan
Yaling Han
ResearchOpen Access30 Apr 2022
Cell Death & Disease

Volume: 13, P: 1-13
CREG ameliorates the phenotypic switching of cardiac fibroblasts after myocardial infarction via modulation of CDC42

Dan Liu
Xiaoxiang Tian
Yaling Han
ResearchOpen Access06 Apr 2021
Cell Death & Disease

Volume: 12, P: 1-16
MiR-221-3p targets Hif-1α to inhibit angiogenesis in heart failure

This study describes how miR-221-3p in endothelial cells reduces angiogenesis by inhibiting hypoxia-inducible factor-1α. Because antagonism of miR-221-3p significantly improves the cardiac function of mice with heart failure it may be a new and effective molecular target for progressing and treatment of heart failure.

Yuying Li
Chenghui Yan
Yaling Han
Research01 Sept 2020
Laboratory Investigation

Volume: 101, P: 104-115

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S100A12 triggers NETosis to aggravate myocardial infarction injury via the Annexin A5-calcium axis

Association of hemoglobin with decreased prevalence of diabetic retinopathy among Tibetan male patients

Single-cell transcriptomics in MI identify Slc25a4 as a new modulator of mitochondrial malfunction and apoptosis-associated cardiomyocyte subcluster

Genome sequence and genetic diversity of the common carp, Cyprinus carpio

Efficient oxygen evolution electrocatalysis in acid by a perovskite with face-sharing IrO₆ octahedral dimers

Potential therapeutic targets for COVID-19 complicated with pulmonary hypertension: a bioinformatics and early validation study

FGF21-FGFR1 controls mitochondrial homeostasis in cardiomyocytes by modulating the degradation of OPA1

Tumor-derived HMGB1 induces CD62L^dim neutrophil polarization and promotes lung metastasis in triple-negative breast cancer

Identification of critical endoplasmic reticulum stress-related genes in advanced atherosclerotic plaque

Recurrent RNA edits in human preimplantation potentially enhance maternal mRNA clearance

Identification of hub modules and therapeutic targets associated with CD8⁺T-cells in HF and their pan-cancer analysis

Unraveling shared molecular signatures and potential therapeutic targets linking psoriasis and acute myocardial infarction

Assessing generalisability of deep learning-based polyp detection and segmentation methods through a computer vision challenge

Unraveling the molecular links between benzopyrene exposure, NASH, and HCC: an integrated bioinformatics and experimental study

Bioinformatics analyses of potentially common pathogenic networks for primary Sjögren’s syndrome complicated with acute myocardial infarction

The CREG1-FBXO27-LAMP2 axis alleviates diabetic cardiomyopathy by promoting autophagy in cardiomyocytes

Exploring shared therapeutic targets in diabetic cardiomyopathy and diabetic foot ulcers through bioinformatics analysis

GCN5-mediated regulation of pathological cardiac hypertrophy via activation of the TAK1-JNK/p38 signaling pathway

CREG ameliorates the phenotypic switching of cardiac fibroblasts after myocardial infarction via modulation of CDC42

MiR-221-3p targets Hif-1α to inhibit angiogenesis in heart failure

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