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Showing 1–2 of 2 results
Advanced filters: Author: Chenguang Lou Clear advanced filters

  • Peptide and oligonucleotide systems are known to self-assemble both in nature and artificial systems. Here, the authors combine both forms of self-assembly through the synthesis of peptideoligonucleotide conjugates and show formation of a three-helix structure that dimerises at higher concentrations.

    • Chenguang Lou
    • Manuel C. Martos-Maldonado
    • Knud J. Jensen
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-9

  • Chiral communication can propagate in secondary structures within the effective intermolecular force (IMF) range but it is not known whether long-range chiral communication exists between tertiary peptide structures. Here, the authors use single-molecule force spectroscopy to investigate chiral interaction between DNA duplexes/triplexes and peptide coiled-coils and demonstrate chiral communication beyond the IMF distance.

    • Shankar Pandey
    • Shankar Mandal
    • Hanbin Mao
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-11