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Showing 1–3 of 3 results
Advanced filters: Author: Cheyenne Rechsteiner Clear advanced filters

  • Rechsteiner and colleagues explore how studying lifespan and disease resistance across species reveals natural adaptations that promote longevity. The authors summarize new discoveries and discuss approaches and recommendations for comparative aging research.

    • Cheyenne Rechsteiner
    • Francesco Morandini
    • Vera Gorbunova
    Reviews
    Nature Aging
    Volume: 5, P: 1686-1703

  • Transposable elements activate during aging with negative consequences. Morandini et al. show that transposons show rapid loss of methylation in peripheral blood mononuclear cells during aging and that models trained on transposon methylation accurately predict age.

    • Francesco Morandini
    • Jinlong Y. Lu
    • Vera Gorbunova
    ResearchOpen Access
    Nature Aging
    Volume: 5, P: 193-204

  • Partial reprogramming to enhance regeneration and mitigate age-related phenotypes is limited by toxicity. Parras et al. report a transgenic reprogrammable mouse strain with attenuated toxicity, by avoiding OSKM expression in the liver and intestine.

    • Alberto Parras
    • Alba Vílchez-Acosta
    • Alejandro Ocampo
    Research
    Nature Aging
    Volume: 3, P: 1509-1520