Here the authors show that human telomerase biogenesis involves LARP3, LARP7, and MePCE mediating the maturation of human telomerase RNA. This study provides insights into the pathogenesis of LARP3 and LARP7/MePCE deficiencies.
- Tsai-Ling Kao
- Yu-Cheng Huang
- Chi-Kang Tseng