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Showing 1–3 of 3 results
Advanced filters: Author: Chiadi Ndumele Clear advanced filters

  • When tested in a multiethnic cohort of ~2.5 million US veterans, the PREVENT equations, recently developed by the American Heart Association for sex-specific and race-free prediction of cardiovascular disease risk, were shown to accurately estimate this risk with some variability across race and ethnicity groups and to outperform the previously used pooled cohort equation risk score.

    • Roy O. Mathew
    • Sadiya S. Khan
    • Janani Rangaswami
    Research
    Nature Medicine
    Volume: 31, P: 2655-2662

  • The pathobiology of heart failure (HF) is incompletely understood. The authors identify 37 circulating proteins and 5 protein modules associated with HF risk, with several demonstrating causal effects on HF, risk factors, or cardiac dysfunction by Mendelian randomization analysis.

    • Amil M. Shah
    • Peder L. Myhre
    • Bing Yu
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-18

  • The metabolic syndrome (MetS) is a diagnosis that groups several risk factors (including abdominal obesity, dysglycaemia, dyslipidaemia and elevated blood pressure) that increase the risk for cardiovascular disease and other health outcomes. This Primer outlines the evolving definition of MetS and describes the pathophysiology, epidemiology, diagnostic criteria and management strategies.

    • Ian J. Neeland
    • Soo Lim
    • Jean-Pierre Després
    Reviews
    Nature Reviews Disease Primers
    Volume: 10, P: 1-22