Repressive histone Lys methyltransferases (KMTs) mediate gene silencing by methylating histone H3 Lys 9 (H3K9), H3K27 and H4K20. Progress has been made in our understanding of the biochemical and functional properties of KMTs, the mechanisms of their recruitment to chromatin and the interplay between them.
- Chiara Mozzetta
- Ekaterina Boyarchuk
- Slimane Ait-Si-Ali