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Scientific Reports (11)
The ISME Journal (4)
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Showing 1–31 of 31 results

Advanced filters: Author: Chih-Hao Lu Clear advanced filters

FCHo2, not talin, enables inside-out activation of integrin ɑvβ5 in curved adhesions

Talin has been believed to be indispensable for integrin activation. Here, the authors show that the curvature-sensing protein FCHo2, not talin, enables inside-out activation of integrin ɑvβ5 in curved adhesions formed at curved membranes.

Chih-Hao Lu
Christina E. Lee
Bianxiao Cui
ResearchOpen Access06 Feb 2026
Nature Communications

Volume: 17, P: 1-20
Room temperature operation of germanium–silicon single-photon avalanche diode

A germanium–silicon single-photon avalanche diode operated at room temperature shows a noise-equivalent power improvement over the previous Ge-based single-photon avalanche diodes by 2–3.5 orders of magnitude.

Neil Na
Yen-Cheng Lu
Shu-Lu Chen
Research21 Feb 2024
Nature

Volume: 627, P: 295-300
Inhibition of ADAM9 promotes the selective degradation of KRAS and sensitizes pancreatic cancers to chemotherapy

Huang et al. show that ADAM9 loss upregulates PAI-1, promoting its interaction with KRAS and resulting in selective lysosomal degradation of KRAS. They also identify a small-molecule inhibitor of ADAM9 with therapeutic benefits in the context of PDAC.

Yu-Kai Huang
Wei-Chung Cheng
Yuh-Pyng Sher
Research24 Jan 2024
Nature Cancer

Volume: 5, P: 400-419
Curved adhesions mediate cell attachment to soft matrix fibres in three dimensions

Zhang et al. report curved adhesions, which are integrin-based adhesions formed in response to membrane curvatures that can be imposed by the overlying extracellular matrix fibre geometry.

Wei Zhang
Chih-Hao Lu
Bianxiao Cui
ResearchOpen Access28 Sept 2023
Nature Cell Biology

Volume: 25, P: 1453-1464
Plasma membrane curvature regulates the formation of contacts with the endoplasmic reticulum

Yang et al. show that plasma membrane curvature promotes the site-specific formation of contacts with the endoplasmic reticulum through junctophilin-2 tethers in cardiomyocytes.

Yang Yang
Luis A. Valencia
Bianxiao Cui
ResearchOpen Access17 Sept 2024
Nature Cell Biology

Volume: 26, P: 1878-1891
Photon deceleration in plasma wakes generates single-cycle relativistic tunable infrared pulses

Plasma can act as strong nonlinear refractive index medium that can be exploited to downshift the frequency of a laser pulse. Here, the authors show the generation of single-cycle tunable infrared pulses using strong density gradients associated with laser-produced wakes in plasmas.

Zan Nie
Chih-Hao Pai
Chan Joshi
ResearchOpen Access03 Jun 2020
Nature Communications

Volume: 11, P: 1-8
Observations on the long-lived Mossbauer effects of ^93mNb

Yao Cheng
Shi-Hui Yang
Chih-Hao Lee
ResearchOpen Access08 Nov 2016
Scientific Reports

Volume: 6, P: 1-8
Author Correction: Plasma membrane curvature regulates the formation of contacts with the endoplasmic reticulum

Yang Yang
Luis A. Valencia
Bianxiao Cui
Amendments and CorrectionsOpen Access02 Dec 2024
Nature Cell Biology

Volume: 27, P: 370
Characterization of prokaryotic plankton community structure in the Southern East China Sea using combined 16S-rDNA and 16S-rRNA

Yi-Ting Chang
Po-Yu Liu
Hsiao-Pei Lu
ResearchOpen Access14 Aug 2025
Scientific Reports

Volume: 15, P: 1-15
Membrane curvature regulates the spatial distribution of bulky glycoproteins

MUC1 is a heavily glycosylated protein on the cell surface. Here the authors show that MUC1 prefers negative over positive membrane curvature due to its bulky size, enabling MUC1 to avoid endocytosis and surface removal based on curvature preference.

Chih-Hao Lu
Kayvon Pedram
Bianxiao Cui
ResearchOpen Access02 Jun 2022
Nature Communications

Volume: 13, P: 1-16
Relativistic single-cycle tunable infrared pulses generated from a tailored plasma density structure

A scheme for generating intense single-cycle pulses in the 5–14 μm wavelength range is proposed. The generation mechanism is described by photon frequency downshifting of an off-the-shelf Ti:sapphire laser in a tailored plasma density structure.

Zan Nie
Chih-Hao Pai
Chan Joshi
Research11 Jun 2018
Nature Photonics

Volume: 12, P: 489-494
Ferroptosis biomarkers predict the outcomes of patients with acute ischemic stroke undergoing endovascular thrombectomy

Shin-Joe Yeh
Chih-Hao Chen
Jiann-Shing Jeng
ResearchOpen Access11 Nov 2025
Scientific Reports

Volume: 15, P: 1-9
Inferring causal molecular networks: empirical assessment through a community-based effort

The HPN-DREAM community challenge assessed the ability of computational methods to infer causal molecular networks, focusing specifically on the task of inferring causal protein signaling networks in cancer cell lines.

Steven M Hill
Laura M Heiser
Sach Mukherjee
ResearchOpen Access22 Feb 2016
Nature Methods

Volume: 13, P: 310-318
High-throughput injection–acceleration of electron bunches from a linear accelerator to a laser wakefield accelerator

Previously, injections from a conventional accelerator into a plasma-based one suffered from low coupling efficiencies. Now electron bunches are injected with an efficiency of nearly 100% into a laser wakefield accelerator without loss of charge.

Yipeng Wu
Jianfei Hua
Chan Joshi
Research18 Mar 2021
Nature Physics

Volume: 17, P: 801-806
RecA-SSB Interaction Modulates RecA Nucleoprotein Filament Formation on SSB-Wrapped DNA

Hung-Yi Wu
Chih-Hao Lu
Hung-Wen Li
ResearchOpen Access19 Sept 2017
Scientific Reports

Volume: 7, P: 1-13
Stable Nuclei of Nucleoprotein Filament and High ssDNA Binding Affinity Contribute to Enhanced RecA E38K Recombinase Activity

Chih-Hao Lu
Ting-Tzu Chang
Hung-Wen Li
ResearchOpen Access02 Nov 2017
Scientific Reports

Volume: 7, P: 1-12
Bioenergetically constrained dynamical microbial interactions govern the performance and stability of methane-producing bioreactors

Chao-Jui Chang
Chun-Wei Chang
Jer-Horng Wu
ResearchOpen Access19 Feb 2025
npj Biofilms and Microbiomes

Volume: 11, P: 1-12
The structure-based cancer-related single amino acid variation prediction

Jia-Jun Liu
Chin-Sheng Yu
Chih-Hao Lu
ResearchOpen Access30 Jun 2021
Scientific Reports

Volume: 11, P: 1-17
Nanoscale in silico and in vitro modeling of lipid bilayers for curvature induction and sensing

Ghafar Yerima
Ching-Ting Tsai
Mohammad R. K. Mofrad
ResearchOpen Access02 Dec 2024
npj Biological Physics and Mechanics

Volume: 1, P: 1-11
In vitro characterization of a small molecule PD-1 inhibitor that targets the PD-l/PD-L1 interaction

Chih-Hao Lu
Wei-Min Chung
Huey-En Tzeng
ResearchOpen Access07 Jan 2022
Scientific Reports

Volume: 12, P: 1-11
Potent sialic acid inhibitors that target influenza A virus hemagglutinin

Yu-Jen Chang
Cheng-Yun Yeh
Chih-Hao Lu
ResearchOpen Access21 Apr 2021
Scientific Reports

Volume: 11, P: 1-11
Evolutionary constraints on species diversity in marine bacterioplankton communities

Hsiao-Pei Lu
Yi-Chun Yeh
Chih-hao Hsieh
Research03 Jan 2019
The ISME Journal

Volume: 13, P: 1032-1041
High-resolution phase-contrast imaging of biological specimens using a stable betatron X-ray source in the multiple-exposure mode

Bo Guo
Xiaohui Zhang
Wei Lu
ResearchOpen Access24 May 2019
Scientific Reports

Volume: 9, P: 1-10
USP17 mediates macrophage-promoted inflammation and stemness in lung cancer cells by regulating TRAF2/TRAF3 complex formation

Chih-Hao Lu
Da-Wei Yeh
Tsung-Hsien Chuang
ResearchOpen Access23 Jul 2018
Oncogene

Volume: 37, P: 6327-6340
Spatial heterogeneity of gut microbiota reveals multiple bacterial communities with distinct characteristics

Hsiao-Pei Lu
Yung-Chih Lai
Hon-Tsen Yu
ResearchOpen Access26 Aug 2014
Scientific Reports

Volume: 4, P: 1-8
CpG-oligodeoxynucleotides developed for grouper toll-like receptor (TLR) 21s effectively activate mouse and human TLR9s mediated immune responses

Da-Wei Yeh
Chao-Yang Lai
Tsung-Hsien Chuang
ResearchOpen Access11 Dec 2017
Scientific Reports

Volume: 7, P: 1-10
Predator and prey biodiversity relationship and its consequences on marine ecosystem functioning—interplay between nanoflagellates and bacterioplankton

Jinny Wu Yang
Wenxue Wu
Chih-hao Hsieh
Research27 Apr 2018
The ISME Journal

Volume: 12, P: 1532-1542
Acute Stress Impairs Hippocampal Mossy Fiber-CA3 Long-Term Potentiation by Enhancing cAMP-Specific Phosphodiesterase 4 Activity

Chien-Chung Chen
Chih-Hao Yang
Kuei-Sen Hsu
Research17 Mar 2010
Neuropsychopharmacology

Volume: 35, P: 1605-1617
Correction: USP17 mediates macrophage-promoted inflammation and stemness in lung cancer cells by regulating TRAF2/TRAF3 complex formation

Chih-Hao Lu
Da-Wei Yeh
Tsung-Hsien Chuang
Amendments and CorrectionsOpen Access30 May 2019
Oncogene

Volume: 38, P: 5742-5743
Evaluating community–environment relationships along fine to broad taxonomic resolutions reveals evolutionary forces underlying community assembly

Hsiao-Pei Lu
Yi-Chun Yeh
Chih-hao Hsieh
Research13 May 2016
The ISME Journal

Volume: 10, P: 2867-2878
Contrasting the relative importance of species sorting and dispersal limitation in shaping marine bacterial versus protist communities

Wenxue Wu
Hsiao-Pei Lu
Chih-Hao Hsieh
Research10 Nov 2017
The ISME Journal

Volume: 12, P: 485-494