Constructing synthetic mimics of membraneless organelles using small molecules can contribute towards our understanding of active phase separation and their role in the chemical emergence of compartments. Herein, the authors develop a model of synthetic membraneless organelles as non-equilibrium droplet phase which are accessed via homotypic interactions between small activated molecule and short peptides.
- Saurabh Gupta
- Sangam Jha
- Dibyendu Das