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Showing 1–2 of 2 results
Advanced filters: Author: Chittampalli Yashaswini Clear advanced filters

  • Metastatic dissemination contributes to the lethality in pancreatic ductal adenocarcinoma (PDAC). Here, the authors perform RNA-sequencing on patient derived circulating tumor cells (CTCs) and identify three major CTC subgroups, and show the therapeutic potential of targeting LIN28B/let-7 pathway to halt cancer metastasis.

    • Joseph W. Franses
    • Julia Philipp
    • David T. Ting
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-12

  • Hepatic stellate cells (HSCs) drive liver fibrosis and are closely linked to liver cancer development. This comprehensive Review provides an in-depth analysis of the specific characteristics of HSCs in cancer, highlighting therapeutic implications based on progress in clarifying HSC biology.

    • Bruno Cogliati
    • Chittampalli N. Yashaswini
    • Scott L. Friedman
    Reviews
    Nature Reviews Gastroenterology & Hepatology
    Volume: 20, P: 647-661