Nature Search

CD14 Modulates PI3K/AKT/p38-MAPK Licensing of Negative Regulators of TLR Signaling to Restrain Chronic Inflammation

Bikash Sahay
Rebeca Patsey
Timothy Sellati
ResearchOpen Access25 Jun 2008
Nature Precedings

P: 1
Diagnostic accuracy of multiplex polymerase chain reaction on tissue biopsies in periprosthetic joint infections

Igor Lazic
Susanne Feihl
Christian Suren
ResearchOpen Access30 Sept 2021
Scientific Reports

Volume: 11, P: 1-6
Benchmarking tomographic acquisition schemes for high-resolution structural biology

Here the authors systematically benchmark cryo-electron tomography acquisition schemes to optimize the attainable resolution for subtomogram averaging, and find that dose-symmetric acquisition with even angular sampling provides a better outcome than most currently used acquisition schemes.

Beata Turoňová
Wim J. H. Hagen
Martin Beck
ResearchOpen Access13 Feb 2020
Nature Communications

Volume: 11, P: 1-9
Bactericidal effect of tetracycline in E. coli strain ED1a may be associated with ribosome dysfunction

The human gut contains diverse bacterial strains that are beneficial/critical for health. Here, the authors compare the response of human gut and laboratory E. coli strains to the antibiotic tetracycline in molecular detail and find a severe dysfunction of protein synthesis only in the gut strain.

Iskander Khusainov
Natalie Romanov
Martin Beck
ResearchOpen Access05 Jun 2024
Nature Communications

Volume: 15, P: 1-15
Nuclear pores safeguard the integrity of the nuclear envelope

Taniguchi et al. structurally analyse nuclear pore complex architecture in situ during differentiation, which is associated with mechanical constraints on the nuclear envelope. They link nuclear pore complex elasticity to nuclear envelope integrity in differentiation.

Reiya Taniguchi
Clarisse Orniacki
Martin Beck
ResearchOpen Access09 Apr 2025
Nature Cell Biology

Volume: 27, P: 762-775
In-cell architecture of the nuclear pore and snapshots of its turnover

In-cell structural studies in Saccharomyces cerevisiae reveal that the configuration of the Nup159 complex is a key determinant of the mRNA export function of the nuclear pore complex, and suggest a model in which nuclear pore complexes are degraded via the autophagy machinery.

Matteo Allegretti
Christian E. Zimmerli
Martin Beck
Research02 Sept 2020
Nature

Volume: 586, P: 796-800
Convolutional networks for supervised mining of molecular patterns within cellular context

DeePiCt (deep picker in context) is a versatile, open-source deep-learning framework for supervised segmentation and localization of subcellular organelles and biomolecular complexes in cryo-electron tomography.

Irene de Teresa-Trueba
Sara K. Goetz
Judith B. Zaugg
ResearchOpen Access23 Jan 2023
Nature Methods

Volume: 20, P: 284-294
Dual roles of mTORC1-dependent activation of the ubiquitin-proteasome system in muscle proteostasis

Exploring the relationship between mTORC1 and the ubiquitin-proteasome system, light is shed on the paradox between mTORC1-mediated muscle hypertrophy induced by PKB/Akt and the muscle atrophy induced by mTORC1 alone.

Marco S. Kaiser
Giulia Milan
Markus A. Rüegg
ResearchOpen Access27 Oct 2022
Communications Biology

Volume: 5, P: 1-18
Proteomics in hypertension

D M Carty
E Schiffer
C Delles
Reviews09 Aug 2012
Journal of Human Hypertension

Volume: 27, P: 211-216

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