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Advanced filters: Author: Christian Schlieker Clear advanced filters

Blocking ubiquitin transfer

The protein OTUB1 inhibits DNA repair without using its enzymatic activity. Instead, it sequesters a protein that is required for the assembly of certain forms of ubiquitin chain, which function as key signals during repair.

April Rose
Christian Schlieker
News & Views18 Aug 2010
Nature

Volume: 466, P: 929-930
Atypical nuclear envelope condensates linked to neurological disorders reveal nucleoporin-directed chaperone activities

Kuiper et al. and Prophet et al. implicate DNAJB6/HSP70 chaperone activities in the biogenesis of the nuclear pore complex permeability barrier and find that disease-linked nuclear envelope blebs are enriched in nucleoporin and chaperone condensates.

Sarah M. Prophet
Anthony J. Rampello
Christian Schlieker
Research27 Oct 2022
Nature Cell Biology

Volume: 24, P: 1630-1641
Substrate recognition by the AAA+ chaperone ClpB

Christian Schlieker
Jimena Weibezahn
Axel Mogk
Research20 Jun 2004
Nature Structural & Molecular Biology

Volume: 11, P: 607-615
Mechanisms, biology and inhibitors of deubiquitinating enzymes

Kerry Routenberg Love
André Catic
Hidde L Ploegh
Reviews18 Oct 2007
Nature Chemical Biology

Volume: 3, P: 697-705
Neural network based successor representations to form cognitive maps of space and language

Paul Stoewer
Christian Schlieker
Patrick Krauss
ResearchOpen Access04 Jul 2022
Scientific Reports

Volume: 12, P: 1-13