Hans-Guido Wendel and colleagues identify five miRNAs that are capable of promoting T-ALL in a mouse model and that account for the majority of miRNA expression in human T-ALL. They show that these miRNAs produce overlapping and cooperative effects on tumor suppressor genes implicated in the pathogenesis of T-ALL.
- Konstantinos J Mavrakis
- Joni Van Der Meulen
- Hans-Guido Wendel
