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Showing 1–4 of 4 results

Advanced filters: Author: Christine A. Codomo Clear advanced filters

CUT&Tag for efficient epigenomic profiling of small samples and single cells

Understanding gene regulation will require mapping specific chromain features in a small number of cells at high resolution. Here the authors describe CUT&Tag, which uses antibody-mediated tethering of Tn5 transposase to a chromatin protein to generate high resolution libraries.

Hatice S. Kaya-Okur
Steven J. Wu
Steven Henikoff
ResearchOpen Access29 Apr 2019
Nature Communications

Volume: 10, P: 1-10
Multifactorial profiling of epigenetic landscapes at single-cell resolution using MulTI-Tag

A scalable barcoding method measures multiple chromatin-associated proteins in single cells.

Michael P. Meers
Geneva Llagas
Steven Henikoff
ResearchOpen Access31 Oct 2022
Nature Biotechnology

Volume: 41, P: 708-716
CENP-A octamers do not confer a reduction in nucleosome height by AFM

Christine A Codomo
Takehito Furuyama
Steven Henikoff
Correspondence06 Jan 2014
Nature Structural & Molecular Biology

Volume: 21, P: 4-5
Scalable single-cell profiling of chromatin modifications with sciCUT&Tag

This protocol provides guidelines for performing single-cell combinatorial indexing cleavage under targets and tagmentation. This method builds on the existing cleavage under targets and tagmentation method and uses a combinatorial indexing step to allow single-cell profiling of chromatin modifications.

Derek H. Janssens
Jacob E. Greene
Steven Henikoff
Protocols07 Nov 2023
Nature Protocols

Volume: 19, P: 83-112