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Showing 1–2 of 2 results
Advanced filters: Author: Christoph Hirche Clear advanced filters

  • Velten et al. use single-cell transcriptomics and functional data to map the early lineage commitment of human haematopoietic stem cells as a continuous process of cells passing through transitory states rather than demarcating discrete progenitors.

    • Lars Velten
    • Simon F. Haas
    • Lars M. Steinmetz
    Research
    Nature Cell Biology
    Volume: 19, P: 271-281

  • Innate immune signaling pathways sense different microbial features and can elicit distinct yet overlapping immune responses. Here the authors dissect the contribution of these pathways to the response to MCMV infection and find that STING signaling is dispensable for host survival but crucial to restrict viral replication and dissemination via myeloid cells.

    • Pia-Katharina Tegtmeyer
    • Julia Spanier
    • Ulrich Kalinke
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-12